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Symbol Name ID |
Sptlc2
serine palmitoyltransferase, long chain base subunit 2 MGI:108074 |
| Darker colors indicate more annotations |
| Human Phenotypes | Osteomyelitis |
| Disease(s) Associated with SPTLC2 | |
| hereditary sensory and autonomic neuropathy type 1C |
| Mouse Phenotypes | abnormal thymus morphology |
decreased thymus weight |
increased neutrophil cell number |
increased dendritic cell number |
increased T-helper 17 cell number |
increased gamma-delta T cell number |
decreased lymphocyte cell number |
abnormal Langerhans cell morphology |
abnormal dendritic epidermal T cell morphology |
abnormal spleen morphology |
decreased spleen weight |
abnormal Langerhans cell physiology |
skin inflammation |
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| Availability | Mouse Genotype | |||||||||||||
| Sptlc2tm1Yhir/Sptlc2tm1Yhir Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ (conditional) |
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| Sptlc2tm1Yhir/Sptlc2tm1Yhir Tg(KRT5-cre)1Tak/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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